⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910259 | 0.76 | — | — | |
| SCHEMBL8539819 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL128926 | 0.67 | — | — | |
| SCHEMBL7285343 | 0.67 | — | — | |
| SCHEMBL28279495 | 0.67 | — | — | |
| SCHEMBL2226243 | 0.65 | — | — | |
| SCHEMBL8538285 | 0.65 | — | — | |
| SCHEMBL9509371 | 0.64 | — | — | |
| SCHEMBL691901 | 0.64 | — | — | |
| SCHEMBL28231931 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508403-A | ENHANCES EFFECTS OF ANTITUMOR AGENTS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0353692-B1 | Drug effect-enhancing agent for antitumor drug | NISSAN CHEMICAL IND LTD (JP) | 1995-10-04 | — | — | EP | disclosed |
| EP-0655455-A1 | Novel phosporus containing pyridine derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-05-31 | — | — | EP | disclosed |
| US-5304550-A | Synergistic | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5130303-A | Pyridine derivative administering | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0353692-A2 | Drug effect-enhancing agent for antitumor drug | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-02-07 | — | — | EP | disclosed |