SCHEMBL728671

SCHEMBL728671

CCOC(=O)CC(C(=O)OCC)N(C[SiH](OCC)OCC)OC

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
CYP3A4 P08684 2/20 0.37
ALOX15 P16050 2/20 0.37
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
CHRM1 P11229 1/20 0.36
ADORA1 P30542 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
TRPA1 O75762 1/20 0.32
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15900030 0.71 MGAM (0.44) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL27464792 0.70 GAA (0.43) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL730161 0.68 ALDH1A1 (0.36) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL4268625 0.67 ALDH1A1 (0.40) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL4268633 0.67 ALDH1A1 (0.40) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL4266370 0.67 ALDH1A1 (0.37) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL4266359 0.67 ALDH1A1 (0.37) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL4261171 0.66 ALDH1A1 (0.39) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL4261167 0.66 ALDH1A1 (0.39) ALDH1A1CYP3A4ALOX15TSHRTDP1
SCHEMBL730206 0.64 ALDH1A1 (0.37) ALDH1A1CYP3A4ALOX15TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed