SCHEMBL7286809

SCHEMBL7286809

NC(=NCCC(c1ccccc1)c1ccc(Cl)cc1)NCCCc1c[nH]cn1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.43
MAOA P21397 2/20 0.43
MAOB P27338 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9828417 0.94 KDM1A (0.47) KDM1AMAOAMAOB
SCHEMBL7295398 0.92
SCHEMBL7285773 0.91 KDM1A (0.40) KDM1AMAOAMAOB
SCHEMBL7285534 0.90 KDM1A (0.43) KDM1AMAOAMAOB
SCHEMBL9828132 0.89 KDM1A (0.44) KDM1AMAOAMAOB
SCHEMBL7285354 0.87 NPY1R (0.40)
SCHEMBL9827666 0.86 NPY1R (0.49)
SCHEMBL7433411 0.86
SCHEMBL9710041 0.84 NPY1R (0.54)
SCHEMBL7285224 0.84 NPY1R (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262448-B1 IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM HEUMANN PHARMA GMBH & CO (DE) 1991-12-18 EP disclosed