⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5848795 | 0.97 | — | — | |
| SCHEMBL13628806 | 0.67 | — | — | |
| SCHEMBL13628804 | 0.58 | — | — | |
| SCHEMBL23839081 | 0.58 | DRD3 (0.33) | — | |
| SCHEMBL1760690 | 0.57 | — | — | |
| SCHEMBL19301355 | 0.57 | — | — | |
| SCHEMBL19301253 | 0.57 | — | — | |
| SCHEMBL576319 | 0.57 | — | — | |
| SCHEMBL13186264 | 0.55 | — | — | |
| SCHEMBL25042202 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1559399-A1 | Use of 2-iminothiolane derivatives in hair care products | L'OREAL (FR) | 2005-08-03 | — | — | EP | claimed |
| EP-4606890-A2 | ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS AND METHODS FOR MAKING AND USING THE SAME | President and Fellows of Harvard College (US) | 2025-08-27 | — | — | EP | disclosed |
| EP-3484448-B1 | ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS AND METHODS FOR MAKING AND USING THE SAME | HARVARD COLLEGE (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2023147185-A9 | METHODS FOR MAKING AND USING ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS TO ENHANCE T-CELL THERAPIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-01-04 | — | — | WO | disclosed |
| US-20230340404-A1 | ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS AND METHODS FOR MAKING AND USING THE SAME | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2023147185-A1 | METHODS FOR MAKING AND USING ANTIGEN-PRESENTING CELL-MIMETIC SCAFFOLDS TO ENHANCE T-CELL THERAPIES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-03 | — | — | WO | disclosed |
| US-11555177-B2 | Antigen-presenting cell-mimetic scaffolds and methods for making and using the same | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-01-17 | — | — | US | disclosed |
| CN-115537372-A | Antigen presenting cell mimetic scaffolds and methods of making and using same | 哈佛学院院长等 | 2022-12-30 | — | — | CN | disclosed |
| CN-115404196-A | Antigen presenting cell mimetic scaffolds and methods of making and using same | 哈佛学院院长等 | 2022-11-29 | — | — | CN | disclosed |
| CN-115305229-A | Antigen presenting cell mimetic scaffolds and methods of making and using same | 哈佛学院院长等 | 2022-11-08 | — | — | CN | disclosed |
| US-5621083-A | TREATING AUTOIMMUNE DISEASES, CANCER, GRAFT-VERSUS-HOST DISEASE | XOMA CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| EP-0700444-A1 | IMMUNOTOXINS COMPRISING GELONIN AND AN ANTIBODY | Xoma Corporation (US) | 1996-03-13 | — | — | EP | disclosed |
| EP-0669982-A1 | MATERIALS COMPRISING AND METHODS OF PREPARATION AND USE FOR RIBOSOME-INACTIVATING PROTEINS | Xoma Corporation (US) | 1995-09-06 | — | — | EP | disclosed |
| US-5416202-A | Such as gelonin, cysteine substitution | XOMA CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0669982-A4 | MATERIALS COMPRISING AND METHODS OF PREPARATION AND USE FOR RIBOSOME-INACTIVATING PROTEINS. | XOMA CORP (US) | 1995-01-02 | — | — | EP | disclosed |
| US-5376546-A | Analogs of ribosome-inactivating proteins | XOMA CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| WO-1994026910-A1 | IMMUNOTOXINS COMPRISING GELONIN AND AN ANTIBODY | XOMA CORPORATION (US) | 1994-11-24 | — | — | WO | disclosed |
| EP-0590067-A1 | MICROBIALLY-PRODUCED ANTIBODY FRAGMENTS AND THEIR CONJUGATES | Xoma Corporation (US) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993009130-A1 | MATERIALS COMPRISING AND METHODS OF PREPARATION AND USE FOR RIBOSOME-INACTIVATING PROTEINS | XOMA CORPORATION (US) | 1993-05-13 | — | — | WO | disclosed |
| WO-1992022324-A1 | MICROBIALLY-PRODUCED ANTIBODY FRAGMENTS AND THEIR CONJUGATES | XOMA CORPORATION (US) | 1992-12-23 | — | — | WO | disclosed |