Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295345 | 0.98 | SLC2A1 (0.53) | SLC2A1ABCB1ABCG2ACHECHRM2 | |
| SCHEMBL7283720 | 0.93 | SLC2A1 (0.58) | SLC2A1ABCB1ABCG2CHRM2CHRM1 | |
| SCHEMBL7293467 | 0.84 | SLC2A1 (0.56) | SLC2A1ABCB1ABCG2ACHECHRM2 | |
| SCHEMBL7286452 | 0.83 | SLC2A1 (0.45) | SLC2A1ABCB1ABCG2TAAR1 | |
| Hydrochloric Acid SCHEMBL7292452 | 0.82 | SLC2A1 (0.60) | SLC2A1ABCB1ABCG2ACHETAAR1 | |
| SCHEMBL7293616 | 0.82 | SLC2A1 (0.56) | SLC2A1ABCB1ABCG2ACHECHRM2 | |
| SCHEMBL7285836 | 0.82 | KDM4E (0.48) | SLC2A1ABCB1ABCG2 | |
| Hydrochloric Acid SCHEMBL7292865 | 0.80 | SLC2A1 (0.60) | SLC2A1ABCB1ABCG2CHRM2CHRM1 | |
| SCHEMBL7285255 | 0.80 | SLC2A1 (0.47) | SLC2A1ABCB1ACHETAAR1 | |
| SCHEMBL7279399 | 0.79 | SLC2A1 (0.49) | SLC2A1ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223598-B1 | CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FISONS plc (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4939147-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC. (GB) | 1990-07-03 | — | — | US | disclosed |
| US-4922022-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| US-4883804-A | Aromatic compounds | FISONS PLC (GB) | 1989-11-28 | — | — | US | disclosed |
| EP-0223598-A2 | Catecholamine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-05-27 | — | — | EP | disclosed |