Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286452 | 0.87 | SLC2A1 (0.45) | SLC2A1POLBHTR1AADRA1DADRA1A | |
| SCHEMBL7283720 | 0.87 | SLC2A1 (0.58) | SLC2A1HTR1AABCB1TAAR1 | |
| SCHEMBL7279399 | 0.85 | SLC2A1 (0.49) | SLC2A1POLBABCB1 | |
| SCHEMBL7296118 | 0.84 | SLC2A1 (0.49) | SLC2A1POLBPKMHTR1AADRA1D | |
| SCHEMBL10383098 | 0.83 | SLC2A1 (0.42) | SLC2A1MEN1KMT2ATP53TAAR1 | |
| SCHEMBL7438265 | 0.82 | TUBB4A (0.48) | SLC2A1HTR2AHTR2CHTR2BABCB1 | |
| Hydrochloric Acid SCHEMBL10383913 | 0.82 | SLC2A1 (0.53) | SLC2A1MEN1KMT2ATAAR1 | |
| SCHEMBL7437374 | 0.82 | MAPT (0.48) | SLC2A1POLBHTR1AADRA1DADRA1A | |
| SCHEMBL7285836 | 0.80 | KDM4E (0.48) | SLC2A1MEN1KMT2AABCB1 | |
| SCHEMBL7287145 | 0.80 | SLC2A1 (0.53) | SLC2A1ABCB1ACHETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223598-B1 | CATECHOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FISONS plc (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4939147-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC. (GB) | 1990-07-03 | — | — | US | disclosed |
| US-4922022-A | Substituted 3,4-dihydroxy phenylethylamino compounds | FISONS PLC (GB) | 1990-05-01 | — | — | US | disclosed |
| US-4883804-A | Aromatic compounds | FISONS PLC (GB) | 1989-11-28 | — | — | US | disclosed |
| EP-0223598-A2 | Catecholamine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-05-27 | — | — | EP | disclosed |