Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 19/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287337 | 1.00 | ITGB3 (0.48) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| Hydrochloric Acid SCHEMBL7284193 | 0.99 | ITGB3 (0.48) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| Hydrochloric Acid SCHEMBL7284184 | 0.99 | ITGB3 (0.48) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| SCHEMBL7278333 | 0.94 | ITGB3 (0.43) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| Hydrochloric Acid SCHEMBL7277850 | 0.93 | ITGB3 (0.42) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| SCHEMBL7287318 | 0.83 | ITGB3 (0.45) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| SCHEMBL7924881 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| SCHEMBL7370859 | 0.82 | ITGB3 (0.49) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| Hydrochloric Acid SCHEMBL7275904 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BPLA2G10PLA2G5 | |
| SCHEMBL7277834 | 0.78 | PLA2G10 (0.56) | ITGB3ITGA2BPLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529858-B1 | 2-Piperazinone compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-10-15 | — | — | EP | disclosed |
| US-5294713-A | Inhibiting cell adhesion | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0529858-A1 | 2-Piperazinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |