Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287822 | 0.91 | TSHR (0.44) | TSHRALDH1A1THRBSMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL7287352 | 0.90 | TSHR (0.43) | TSHRALDH1A1THRBSMN1; SMN2NPSR1 | |
| SCHEMBL7288491 | 0.90 | MEN1 (0.44) | TSHRALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7291570 | 0.88 | CMA1 (0.41) | TSHRALDH1A1HTTGSK3BLMNA | |
| SCHEMBL10427988 | 0.83 | TSHR (0.46) | TSHRSMN1; SMN2NPSR1HTTLMNA | |
| SCHEMBL7281531 | 0.82 | MEN1 (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL7288360 | 0.82 | MEN1 (0.46) | TSHRALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7287042 | 0.81 | MEN1 (0.44) | TSHRALDH1A1KMT2AMEN1HTT | |
| SCHEMBL7288565 | 0.81 | ALDH1A1 (0.44) | TSHRALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7288500 | 0.81 | MEN1 (0.43) | TSHRALDH1A1KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |