Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.66 |
| ▸ | CTSL | P07711 | 4/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.62 |
| ▸ | CTSS | P25774 | 3/20 | 0.62 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.59 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287480 | 1.00 | CTSK (0.66) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL7165055 | 0.88 | CTSK (0.66) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL29865964 | 0.87 | CTSK (0.69) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL6495005 | 0.87 | CTSK (0.69) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL9393894 | 0.86 | CAPN1 (0.69) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL7293242 | 0.86 | TACR1 (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL7293246 | 0.86 | TACR1 (0.60) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL8583015 | 0.85 | CTSK (0.66) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL30065522 | 0.85 | CTSK (0.69) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL27493720 | 0.85 | CTSK (0.69) | CTSKCTSLCTSBCTSSCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994025581-A1 | MODIFIED RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR | SOUTHERN SYDNEY AREA HEALTH SERVICE (AU) | 1994-11-10 | — | — | WO | disclosed |
| EP-0263903-A1 | Method for preparing specific inhibitors of virus-specified proteases | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-20 | — | — | EP | disclosed |
| EP-0263214-A1 | Tetrapeptide methyl ketone inhibitors of viral proteases | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0263202-A1 | Inhibition of viral protease activity by peptide halomethyl ketones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-13 | — | — | EP | disclosed |
| US-4652552-A | ENZYME INHIBITORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-24 | — | — | US | disclosed |
| US-4644055-A | HALOMETHYL KETONE OR METHYL KETONE COVALENTLY LINKED TO PEPTIDE SEQUENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-17 | — | — | US | disclosed |
| US-4636492-A | ENZYME INHIBITORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |