Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295718 | 0.91 | NAAA (0.60) | NAAASMN1; SMN2PRKCAALDH1A1 | |
| SCHEMBL8690279 | 0.81 | NAAA (0.72) | NAAASMN1; SMN2PRKCAALDH1A1 | |
| SCHEMBL7288042 | 0.81 | NAAA (0.72) | NAAASMN1; SMN2PRKCAALDH1A1 | |
| SCHEMBL7296912 | 0.80 | NAAA (0.49) | NAAASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL17218924 | 0.78 | NAAA (0.55) | NAAASMN1; SMN2PRKCAALDH1A1 | |
| SCHEMBL27453624 | 0.78 | NAAA (0.54) | NAAASMN1; SMN2PRKCAALDH1A1TP53 | |
| SCHEMBL10692599 | 0.77 | NAAA (0.61) | NAAASMN1; SMN2PRKCAALDH1A1TP53 | |
| SCHEMBL10692605 | 0.77 | NAAA (0.61) | NAAASMN1; SMN2PRKCAALDH1A1TP53 | |
| SCHEMBL11406577 | 0.76 | NAAA (0.53) | NAAASMN1; SMN2PRKCAALDH1A1 | |
| SCHEMBL4978268 | 0.76 | NAAA (0.82) | NAAASMN1; SMN2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |