Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286690 | 0.91 | REN (0.60) | REN | |
| SCHEMBL7280686 | 0.90 | REN (0.57) | REN | |
| SCHEMBL7278096 | 0.90 | REN (0.67) | REN | |
| SCHEMBL7280853 | 0.89 | REN (0.67) | REN | |
| SCHEMBL7286773 | 0.85 | REN (0.47) | REN | |
| SCHEMBL7288675 | 0.85 | REN (0.55) | REN | |
| SCHEMBL7287494 | 0.83 | REN (0.62) | REN | |
| SCHEMBL7280012 | 0.83 | REN (0.62) | REN | |
| SCHEMBL7280335 | 0.83 | REN (0.61) | REN | |
| SCHEMBL7393260 | 0.83 | REN (0.63) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589446-A1 | N-(Hydroxyethyl)butanediamide derivatives as renin inhibitors | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1994-03-30 | — | — | EP | claimed |