⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72375 | 1.00 | — | — | |
| SCHEMBL731350 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4090424 | 0.97 | GAA (0.32) | — | |
| Hydrochloric Acid SCHEMBL27676966 | 0.97 | GAA (0.32) | — | |
| SCHEMBL2336833 | 0.82 | — | — | |
| SCHEMBL10401754 | 0.80 | POLB (0.32) | — | |
| SCHEMBL11350359 | 0.71 | — | — | |
| SCHEMBL6152816 | 0.69 | — | — | |
| SCHEMBL5180410 | 0.69 | — | — | |
| SCHEMBL4279010 | 0.67 | SLC18A3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6056830-A | — | — | None | — | — | JP | disclosed |
| US-12527776-B2 | Treatment of ciliopathies using inhibitors of glucosylceramide synthase (GCS) | GENZYME CORPORATION (US) | 2026-01-20 | — | — | US | disclosed |
| EP-4626424-A1 | VENGLUSTAT IN COMBINATION WITH A STRONG OR MODERATE INHIBITOR OF CYP3A4 | GENZYME CORPORATION (US) | 2025-10-08 | — | — | EP | disclosed |
| EP-3920912-B1 | TREATMENT OF CILIOPATHIES USING INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE (GCS) | GENZYME CORP (US) | 2025-06-11 | — | — | EP | disclosed |
| US-12083115-B2 | Methods for treating neurological symptoms associated with lysosomal storage diseases | GENZYME CORPORATION (US) | 2024-09-10 | — | — | US | disclosed |
| WO-2024116127-A1 | VENGLUSTAT IN COMBINATION WITH A STRONG OR MODERATE INHIBITOR OF CYP3A4 | GENZYME CORPORATION (US) | 2024-06-06 | — | — | WO | disclosed |
| EP-4349408-A2 | METHODS FOR TREATING PROTEINOPATHIES | Genzyme Corporation (US) | 2024-04-10 | — | — | EP | disclosed |
| EP-3267983-B1 | METHODS FOR TREATING PROTEINOPATHIES | GENZYME CORP (US) | 2023-12-20 | — | — | EP | disclosed |
| EP-3514157-B1 | METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORP (US) | 2023-09-06 | — | — | EP | disclosed |
| US-20230118142-A1 | AGENTS FOR USE IN THE TREATMENT OF TISSUE DAMAGE | UCL BUSINESS LTD (GB) | 2023-04-20 | — | — | US | disclosed |
| US-5888804-A | SIMPLE AND EFFICIENT BIOSYNTHESIS BY INCUBATING MICROORGANISM WITB QUINUCLIDINONE, RECOVERING OR HARVESTING PRODUCT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0863212-A2 | Processes for production of optical active quinuclidinol | Daicel Chemical Industries, Ltd. (JP) | 1998-09-09 | — | — | EP | disclosed |
| EP-0838448-A1 | Process for the separation of a mixture of enantiomers | DSM N.V. (NL) | 1998-04-29 | — | — | EP | disclosed |
| US-5637722-A | ALKYLATION OF NUCLEOPHILE WITH ALKYL PROPARGYL XANTHATE | RHONE-POULENC CHIMIE (FR) | 1997-06-10 | — | — | US | disclosed |
| US-5569447-A | TOMOGRAPHIC IMAGING AGENTS | THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-10-29 | — | — | US | disclosed |
| US-5387409-A | Diagnostic imaging agents, e.g. hypoxic tissue; radiotherapy; kits | BRACCO INTERNATIONAL B.V. (NL) | 1995-02-07 | — | — | US | disclosed |
| JP-H0656830-A | METHOD FOR ENANTIOMERICALLY ENRICHING (R,S)-3-QUINUCLIDINOL | BEND RES INC | 1994-03-01 | — | — | JP | disclosed |
| EP-0577253-A2 | Enantiomeric enrichment of (R,S)-3-quinuclidinol | BEND RESEARCH, INC. (US) | 1994-01-05 | — | — | EP | disclosed |
| US-5215918-A | Acid anhydride esterification; preferential enzymatic hydrolysis with a subtilisin protease | BEND RESEARCH, INC. (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0441491-A1 | Boronic acid adducts of rhenium dioxime and technetium-99M dioxime complexes containing a biochemically active group | BRACCO INTERNATIONAL B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |