⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72375 | 1.00 | — | — | |
| SCHEMBL728782 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4090424 | 0.97 | GAA (0.32) | — | |
| Hydrochloric Acid SCHEMBL27676966 | 0.97 | GAA (0.32) | — | |
| SCHEMBL2336833 | 0.82 | — | — | |
| SCHEMBL10401754 | 0.80 | POLB (0.32) | — | |
| SCHEMBL11350359 | 0.71 | — | — | |
| SCHEMBL6152816 | 0.69 | — | — | |
| SCHEMBL5180410 | 0.69 | — | — | |
| SCHEMBL4279010 | 0.67 | SLC18A3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104830814-A | Carbonyl reductase and application thereof in preparation of (R)-quinuclidinol | NANJING ABIOCHEM BIOMEDICAL TECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | claimed |
| US-9018379-B1 | Process of preparing solifenacin or salt thereof, and novel intermediate used in the process | KYUNG DONG PHARM. CO., LTD. (KR) | 2015-04-28 | — | — | US | claimed |
| US-20150112072-A1 | PROCESS OF PREPARING SOLIFENACIN OR SALT THEREOF, AND NOVEL INTERMEDIATE USED IN THE PROCESS | KYUNG DONG PHARM. CO., LTD. (KR) | 2015-04-23 | — | — | US | claimed |
| EP-2831070-A1 | PROCESS OF PREPARING SOLIFENACIN OR SALT THEREOF, AND NOVEL INTERMEDIATE USED IN THE PROCESS | Kyung Dong Pharm. Co., Ltd. (KR) | 2015-02-04 | — | — | EP | claimed |
| CN-103702997-A | Process for the preparation of solifenacin and salts thereof | ISOCHEM SA | 2014-04-02 | — | — | CN | claimed |
| WO-2013147458-A1 | PROCESS OF PREPARING SOLIFENACIN OR SALT THEREOF, AND NOVEL INTERMEDIATE USED IN THE PROCESS | KYUNG DONG PHARM. CO., LTD. (KR) | 2013-10-03 | — | — | WO | claimed |
| CN-113387829-B | Preparation method of shakubiqu | 凯特立斯（深圳）科技有限公司 | 2023-04-07 | — | — | CN | disclosed |
| EP-3256464-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2022-05-11 | — | — | EP | disclosed |
| CN-113387829-A | Preparation method of shakubiqu | 凯特立斯（深圳）科技有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-107207473-B | Compounds having muscarinic receptor antagonist and β 2 adrenergic receptor agonist activity | 奇斯药制品公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-107384885-B | Application of imine reductase and mutant thereof in synthesis of (S) -1-aryl-1, 2, 3, 4-tetrahydroisoquinoline | 武汉大学 | 2019-12-24 | — | — | CN | disclosed |
| CN-106282135-B | It the preparation method of quinine ketoreductase RrQR a kind of and its is applied in preparation (R) -3- quinuclidinol | 河北省科学院生物研究所 | 2019-09-27 | — | — | CN | disclosed |
| WO-2018150437-A1 | A PROCESS FOR PREPARING ACLIDINIUM BROMIDE AND INTERMEDIATES THEREOF | GBR LABORATORIES PVT. LTD (IN) | 2018-08-23 | — | — | WO | disclosed |
| US-5888804-A | SIMPLE AND EFFICIENT BIOSYNTHESIS BY INCUBATING MICROORGANISM WITB QUINUCLIDINONE, RECOVERING OR HARVESTING PRODUCT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0863212-A2 | Processes for production of optical active quinuclidinol | Daicel Chemical Industries, Ltd. (JP) | 1998-09-09 | — | — | EP | disclosed |
| US-5569447-A | TOMOGRAPHIC IMAGING AGENTS | THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-10-29 | — | — | US | disclosed |
| US-5387409-A | Diagnostic imaging agents, e.g. hypoxic tissue; radiotherapy; kits | BRACCO INTERNATIONAL B.V. (NL) | 1995-02-07 | — | — | US | disclosed |
| EP-0577253-A2 | Enantiomeric enrichment of (R,S)-3-quinuclidinol | BEND RESEARCH, INC. (US) | 1994-01-05 | — | — | EP | disclosed |
| US-5215918-A | Acid anhydride esterification; preferential enzymatic hydrolysis with a subtilisin protease | BEND RESEARCH, INC. (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0441491-A1 | Boronic acid adducts of rhenium dioxime and technetium-99M dioxime complexes containing a biochemically active group | BRACCO INTERNATIONAL B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |