Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.57 |
| ▸ | HTR3B | O95264 | 6/20 | 0.57 |
| ▸ | HTR3A | P46098 | 6/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281427 | 0.96 | HTR3A (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7280903 | 0.82 | HTR3A (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29881195 | 0.82 | HTR3A (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7288365 | 0.80 | SERPINH1 (0.38) | HTR3ACYP1A2TSHRHSD17B10GAA | |
| SCHEMBL7279005 | 0.78 | GLA (0.49) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7282398 | 0.76 | HTR2A (0.36) | HTR3ACYP1A2ALOX15TSHRHSD17B10 | |
| Bemesetron SCHEMBL5790539 | 0.73 | CYP2D6 (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Bemesetron SCHEMBL29430183 | 0.73 | CYP2D6 (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Bemesetron SCHEMBL10765684 | 0.73 | CYP2D6 (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Bemesetron SCHEMBL195148 | 0.73 | CYP2D6 (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |