Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CEL | P19835 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29616919 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL18380643 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL11630461 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL8853836 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL8855987 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL4117564 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL4117453 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL11486647 | 0.72 | KDM4E (0.51) | KDM4EALDH1A1ATMHTTRAB9A | |
| SCHEMBL9485334 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1ATMHTTHRH3 | |
| SCHEMBL9791278 | 0.71 | KDM4E (0.44) | KDM4EALDH1A1ATMHTTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300688-A1 | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them | FISONS plc (GB) | 1989-01-25 | — | — | EP | disclosed |