Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295938 | 0.86 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL8400074 | 0.86 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL8396215 | 0.86 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7288790 | 0.82 | MAPT (0.40) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL9195804 | 0.82 | MAPT (0.40) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7380239 | 0.80 | MAPT (0.38) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7291466 | 0.79 | KMT2A (0.37) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7289088 | 0.79 | MAPT (0.37) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7289652 | 0.79 | KMT2A (0.37) | ALDH1A1LMNAHPGDALOX12MAPT | |
| SCHEMBL7293366 | 0.78 | MAPT (0.37) | ALDH1A1LMNAHPGDALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487768-B1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL (JP) | 1995-01-25 | — | — | EP | claimed |
| EP-0487768-A1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-03 | — | — | EP | claimed |
| EP-0281045-B1 | BENZOTHIEPINO (5,4-C) PYRIDAZINE COMPOUNDS AND THEIR PHARMACEUTICAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1991-12-27 | — | — | EP | claimed |
| US-4849421-A | SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-07-18 | — | — | US | claimed |
| EP-0487768-B1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL (JP) | 1995-01-25 | — | — | EP | disclosed |
| EP-0487768-A1 | Pharmaceutical composition with improved dissolution property | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0281045-B1 | BENZOTHIEPINO (5,4-C) PYRIDAZINE COMPOUNDS AND THEIR PHARMACEUTICAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1991-12-27 | — | — | EP | disclosed |
| US-4849421-A | SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0281045-A1 | Benzothiepino (5,4-c) pyridazine compounds and their pharmaceutical uses | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |