Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 5/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298617 | 0.89 | NPY2R (0.59) | NPY2RALOX5GAASMN1; SMN2MAPT | |
| SCHEMBL9736030 | 0.89 | NPY2R (0.59) | NPY2RALOX5GAASMN1; SMN2MAPT | |
| SCHEMBL7290591 | 0.85 | NPY2R (0.61) | NPY2RGAASMN1; SMN2TP53MAPK1 | |
| SCHEMBL7288694 | 0.85 | NPY2R (0.61) | NPY2RGAASMN1; SMN2TP53MAPK1 | |
| SCHEMBL7298449 | 0.82 | NPY2R (0.50) | NPY2RALOX5SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7290248 | 0.80 | NPY2R (0.69) | NPY2RGAASMN1; SMN2MAPK1MAPT | |
| Oxalic Acid SCHEMBL7291345 | 0.76 | NPY2R (0.63) | NPY2RSMN1; SMN2MAPTL3MBTL1KMT2A | |
| SCHEMBL9736552 | 0.74 | NPY2R (0.62) | NPY2RGAASMN1; SMN2TP53MAPK1 | |
| SCHEMBL7288507 | 0.73 | NPY2R (0.58) | NPY2RALOX5SMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL7297699 | 0.73 | MEN1 (0.61) | GAASMN1; SMN2TP53MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | claimed |
| EP-0453658-A2 | Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-10-30 | — | — | EP | claimed |
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0453658-A2 | Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-10-30 | — | — | EP | disclosed |