Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290237 | 0.92 | NPY2R (0.69) | NPY2RSIGMAR1MEN1KMT2ANPC1 | |
| SCHEMBL7290591 | 0.88 | NPY2R (0.61) | NPY2RGAATP53MAPK1SMN1; SMN2 | |
| SCHEMBL7288694 | 0.88 | NPY2R (0.61) | NPY2RGAATP53MAPK1SMN1; SMN2 | |
| SCHEMBL9735019 | 0.87 | NPY2R (0.62) | NPY2RMEN1KMT2ANPC1UBE2N | |
| SCHEMBL7288977 | 0.85 | NPY2R (0.58) | NPY2RMEN1KMT2ANPC1UBE2N | |
| SCHEMBL7290248 | 0.83 | NPY2R (0.69) | NPY2RGAAMAPK1SMN1; SMN2KMT2A | |
| Oxalic Acid SCHEMBL7291345 | 0.81 | NPY2R (0.63) | NPY2RSMN1; SMN2SIGMAR1KMT2AL3MBTL1 | |
| SCHEMBL7297873 | 0.80 | NPY2R (0.67) | NPY2RGAATP53MAPK1SMN1; SMN2 | |
| SCHEMBL7290404 | 0.78 | NPY2R (0.65) | NPY2RGAATP53MAPK1KMT2A | |
| SCHEMBL7290625 | 0.76 | NPY2R (0.62) | NPY2RGAAMAPK1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | claimed |
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | disclosed |