Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 1.00 |
| ▸ | ITGA2B | P08514 | 15/20 | 1.00 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.60 |
| ▸ | CHRNG | P07510 | 3/20 | 0.60 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.60 |
| ▸ | CHRND | Q07001 | 3/20 | 0.60 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7300536 | 0.89 | ITGB3 (0.98) | ITGB3ITGA2BGRIA1 | |
| SCHEMBL7299269 | 0.87 | ITGB3 (0.78) | ITGB3ITGA2B | |
| SCHEMBL7290660 | 0.87 | ITGB3 (0.78) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7294731 | 0.87 | ITGB3 (0.77) | ITGB3ITGA2BCHRNA1CHRNGCHRNB1 | |
| Hydrochloric Acid SCHEMBL7300550 | 0.87 | ITGB3 (0.86) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9306228 | 0.87 | ITGB3 (0.87) | ITGB3ITGA2B | |
| SCHEMBL7299376 | 0.85 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7301594 | 0.85 | ITGB3 (0.98) | ITGB3ITGA2B | |
| SCHEMBL7292505 | 0.85 | ITGB3 (0.80) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7299852 | 0.85 | ITGB3 (0.80) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | claimed |
| EP-0478328-A1 | Novel fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | claimed |
| EP-0478328-B1 | Novel fibrinogen receptor antagonists | MERCK & CO INC (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0478328-A1 | Novel fibrinogen receptor antagonists | MERCK & CO. INC. (US) | 1992-04-01 | — | — | EP | disclosed |