SCHEMBL728970

SCHEMBL728970

NC(=O)NS(=O)(=O)Oc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
MEN1 O00255 1/20 1.00
CA1 P00915 8/20 0.50
CA2 P00918 8/20 0.50
CA9 Q16790 8/20 0.50
CA12 O43570 5/20 0.44
STS P08842 3/20 0.43
TP53 P04637 1/20 0.40
PARP10 Q53GL7 1/20 0.40
SLC40A1 Q9NP59 1/20 0.39
CTNNB1 P35222 1/20 0.38
LMNA P02545 1/20 0.38
PPARG P37231 1/20 0.38
NFE2L2 Q16236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7111521 0.84 KMT2A (0.72) KMT2AMEN1CA1CA2CA9
SCHEMBL15424553 0.81 MEN1 (0.68) KMT2AMEN1CA1CA2CA9
SCHEMBL27029813 0.79 MEN1 (0.66) KMT2AMEN1CA1CA2CA9
SCHEMBL28232247 0.78 KMT2A (0.64) KMT2AMEN1CA1CA2CA9
SCHEMBL27397738 0.78 MEN1 (0.64) KMT2AMEN1CA1CA2CA9
SCHEMBL7532809 0.77 KMT2A (0.62) KMT2AMEN1CA1CA2CA9
SCHEMBL27538987 0.77 KMT2A (0.62) KMT2AMEN1CA1CA2CA9
SCHEMBL15423450 0.77 KMT2A (0.62) KMT2AMEN1CA1CA2CA9
SCHEMBL27259347 0.77 KMT2A (0.62) KMT2AMEN1CA1CA2CA9
SCHEMBL10736241 0.75 KMT2A (0.60) KMT2AMEN1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622401-B2 Soybean variety 01106393 MONSANTO TECHNOLOGY LLC (US) 2026-05-12 US claimed
US-12616153-B2 Soybean variety 01098197 MONSANTO TECHNOLOGY LLC (US) 2026-05-05 US claimed
US-12616151-B2 Soybean variety 01106511 MONSANTO TECHNOLOGY LLC (US) 2026-05-05 US claimed
CN-107698525-B Substituted phenoxyl sulfonylurea compounds and preparation method and application thereof 南开大学 2020-04-21 CN claimed
EP-1008297-B1 Mixtures of herbicides and antidotes BAYER CROPSCIENCE GMBH (DE) 2003-03-19 EP claimed
EP-0492367-B1 Mixtures of herbicides and antidotes AVENTIS CROPSCIENCE GMBH (DE) 2000-09-27 EP claimed
US-5488027-A Herbicide-safener combinations containing sulfonylurea or imidazolinone herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-30 US claimed
JP-4257505-A None JP disclosed
US-11913003-B2 Method for improving soybean transformation efficiency BEIJING DABEINONG BIOTECHNOLOGY CO., LTD. (CN) 2024-02-27 US disclosed
US-20210277406-A1 METHOD FOR IMPROVING SOYBEAN TRANSFORMATION EFFICIENCY BEIJING DABEINONG BIOTECHNOLOGY CO., LTD. (CN) 2021-09-09 US disclosed
CN-107099548-B Method for improving soybean conversion efficiency 北京大北农生物技术有限公司 2020-11-03 CN disclosed
CN-107698525-B Substituted phenoxyl sulfonylurea compounds and preparation method and application thereof 南开大学 2020-04-21 CN disclosed
CN-107698525-B Substituted phenoxyl sulfonylurea compounds and preparation method and application thereof 南开大学 2020-04-21 CN disclosed
US-5102443-A Free-and postemergenc herbicides HOECHST AKTIENGESELLSCHAFT (DE) 1992-04-07 US disclosed
US-4963180-A Heterocyclic-substituted phenylsulfamates, and their use as herbicides and plant growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-16 US disclosed
EP-0388771-A1 Phenoxysulfonylureas based on 3-substituted salicyclic acid alkyl esters, processes for their preparation and their use as herbicides and plant growth regulators Hoechst Schering AgrEvo GmbH (DE) 1990-09-26 EP disclosed
EP-0342568-A1 Heterocyclically substituted phenoxysulfonyl urea, process for their preparation and their use as herbicides or as plant growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1989-11-23 EP disclosed
US-4514214-A Herbicidal sulfamates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-30 US disclosed
US-4475944-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-09 US disclosed
EP-0096593-A2 Herbicidal sulfamates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-12-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616151-B2 Soybean variety 01106511 GNMT, NOTCH4, CNPY2 KMT2A 1649/4885MEN1 4681/4885CA1 2233/4885
US-12622401-B2 Soybean variety 01106393 GNMT, CNPY2, NOTCH4 KMT2A 1874/4885MEN1 4768/4885CA1 2814/4885
US-12616153-B2 Soybean variety 01098197 GNMT, NOTCH4, CNPY2 KMT2A 1848/4885MEN1 4753/4885CA1 2480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.