SCHEMBL729032

SCHEMBL729032

C=CC([SiH3])OC(=O)C=CC=CC

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17701377 0.79 ALDH1A1 (0.32) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL17701376 0.79 ALDH1A1 (0.32) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL1173409 0.74 HCAR2 (0.56) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL4754376 0.74 HCAR2 (0.40) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL1173410 0.74 HCAR2 (0.56) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL4754373 0.74 HCAR2 (0.40) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL170415 0.73
SCHEMBL27771869 0.72 HCAR2 (0.39) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL27771867 0.72 HCAR2 (0.39) ALDH1A1LMNAMAPK1HTTHCAR2
SCHEMBL9446903 0.71 HCAR2 (0.38) ALDH1A1LMNAMAPK1HTTHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200207982-A1 POLYAMIDE BLENDS DOW SILICONES CORP (US) 2020-07-02 US claimed
EP-3655482-A1 POLYAMIDE BLENDS Dow Silicones Corporation (US) 2020-05-27 EP claimed
WO-2019018094-A1 POLYAMIDE BLENDS DOW SILICONES CORPORATION (US) 2019-01-24 WO claimed
EP-2294101-B1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORP (US) 2018-10-17 EP claimed
US-8476375-B2 Polymers modified by silanes DOW CORNING CORPORATION (US) 2013-07-02 US claimed
JP-2011526313-A 2011-10-06 JP claimed
US-20110178198-A1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORPORATION 2011-07-21 US claimed
EP-2294101-A1 POLYMERS MODIFIED BY SILANES Dow Corning Corporation (US) 2011-03-16 EP claimed
WO-2010000479-A1 POLYMERS MODIFIED BY SILANES DOW CORNING CORPORATION (US) 2010-01-07 WO claimed
EP-2665756-B1 METHOD FOR PRODUCING SILYL-FUNCTIONALIZED POLYOLEFINS AND SILYL-FUNCTIONALIZED POLYOLEFINS WITH SILYL MONOMER INCORPORATION DOW SILICONES CORP (US) 2022-03-30 EP disclosed
US-20200207982-A1 POLYAMIDE BLENDS DOW SILICONES CORP (US) 2020-07-02 US disclosed
EP-3655482-A1 POLYAMIDE BLENDS Dow Silicones Corporation (US) 2020-05-27 EP disclosed
WO-2019018094-A1 POLYAMIDE BLENDS DOW SILICONES CORPORATION (US) 2019-01-24 WO disclosed
EP-2294101-B1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORP (US) 2018-10-17 EP disclosed
US-8476375-B2 Polymers modified by silanes DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
WO-2012099882-A2 METHOD FOR PRODUCING SILYL-FUNCTIONALIZED POLYOLEFINS AND SILYL-FUNCTIONALIZED POLYOLEFINS WITH SILYL MONOMER INCORPORATION DOW CORNING CORPORATION (US) 2012-07-26 WO disclosed
WO-2012059529-A1 EPOXIDISED ELASTOMER COMPOSITIONS MODIFIED BY SILANES DOW CORNING CORPORATION (US) 2012-05-10 WO disclosed
US-20110178198-A1 POLYMERS MODIFIED BY SILANES DOW SILICONES CORPORATION 2011-07-21 US disclosed
EP-2294101-A1 POLYMERS MODIFIED BY SILANES Dow Corning Corporation (US) 2011-03-16 EP disclosed
WO-2010000479-A1 POLYMERS MODIFIED BY SILANES DOW CORNING CORPORATION (US) 2010-01-07 WO disclosed