Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297873 | 0.88 | NPY2R (0.67) | NPY2RTP53KMT2AALOX5GAA | |
| SCHEMBL7290248 | 0.87 | NPY2R (0.69) | NPY2RALDH1A1KMT2AL3MBTL1GAA | |
| Oxalic Acid SCHEMBL7291345 | 0.83 | NPY2R (0.63) | NPY2RALDH1A1KMT2AL3MBTL1MAPT | |
| SCHEMBL7290237 | 0.82 | NPY2R (0.69) | NPY2RKMT2AL3MBTL1NPC1 | |
| SCHEMBL7288694 | 0.81 | NPY2R (0.61) | NPY2RALDH1A1TP53KMT2AL3MBTL1 | |
| SCHEMBL7290591 | 0.81 | NPY2R (0.61) | NPY2RALDH1A1TP53KMT2AL3MBTL1 | |
| SCHEMBL9736030 | 0.80 | NPY2R (0.59) | NPY2RALDH1A1KMT2AALOX5GAA | |
| SCHEMBL7298617 | 0.80 | NPY2R (0.59) | NPY2RALDH1A1KMT2AALOX5GAA | |
| SCHEMBL7288507 | 0.80 | NPY2R (0.58) | NPY2RALDH1A1KMT2AL3MBTL1ALOX5 | |
| Hydrochloric Acid SCHEMBL7291470 | 0.79 | NPY2R (0.60) | NPY2RALDH1A1KMT2AEPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0453658-A2 | Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-10-30 | — | — | EP | disclosed |