Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 7/20 | 0.69 |
| ▸ | UBE2N | P61088 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288977 | 0.93 | NPY2R (0.58) | NPY2RUBE2NNPC1KMT2AMEN1 | |
| SCHEMBL9736552 | 0.92 | NPY2R (0.62) | NPY2RUBE2NNPC1KMT2AMEN1 | |
| SCHEMBL9735019 | 0.92 | NPY2R (0.62) | NPY2RUBE2NNPC1KMT2AMEN1 | |
| SCHEMBL7290248 | 0.88 | NPY2R (0.69) | NPY2RKMT2AL3MBTL1PTPRC | |
| Oxalic Acid SCHEMBL7291345 | 0.86 | NPY2R (0.63) | NPY2RKMT2AL3MBTL1PTPRCSIGMAR1 | |
| SCHEMBL7297873 | 0.84 | NPY2R (0.67) | NPY2RKMT2ASIGMAR1 | |
| SCHEMBL7290404 | 0.82 | NPY2R (0.65) | NPY2RNPC1KMT2AL3MBTL1 | |
| SCHEMBL7290591 | 0.82 | NPY2R (0.61) | NPY2RKMT2AMEN1RAD52L3MBTL1 | |
| SCHEMBL7288694 | 0.82 | NPY2R (0.61) | NPY2RKMT2AMEN1RAD52L3MBTL1 | |
| SCHEMBL7290434 | 0.81 | NPY2R (0.96) | NPY2RNPC1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | claimed |
| US-5116851-A | Administering antiischemic and antiarrhythmia agents | E. R. SQUIBB & SONS, INC. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0453658-A2 | Use of substituted anilides and sulfonamides in the treatment of cardiovascular diseases | E.R. SQUIBB & SONS, INC. (US) | 1991-10-30 | — | — | EP | disclosed |