Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14845114 | 0.88 | CLEC4M (0.63) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL774558 | 0.84 | CLEC4M (0.76) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL9829849 | 0.83 | CLEC4M (0.56) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL15999534 | 0.81 | CLEC4M (0.64) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL7291947 | 0.81 | CLEC4M (0.54) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL8085907 | 0.81 | CLEC4M (0.55) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL62162 | 0.79 | CLEC4M (0.52) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL30697790 | 0.79 | CLEC4M (0.62) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL29145962 | 0.79 | CLEC4M (0.62) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL2805448 | 0.78 | CLEC4M (0.67) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |