SCHEMBL7290929

SCHEMBL7290929

NC(=O)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 10/20 0.55
DPP4 P27487 3/20 0.47
DPP8 Q6V1X1 3/20 0.47
DPP9 Q86TI2 3/20 0.47
DPP7 Q9UHL4 3/20 0.47
FAP Q12884 1/20 0.47
PREP P48147 1/20 0.47
ACE P12821 1/20 0.47
KMT2A Q03164 1/20 0.46
KLK7 P49862 1/20 0.46
KLK5 Q9Y337 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25129445 1.00 FKBP1A (0.55) FKBP1ADPP4DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL7275982 0.99 FKBP1A (0.54) FKBP1ADPP4DPP8DPP9DPP7
Trifluoroacetic Acid SCHEMBL29286206 0.94 FKBP1A (0.50) FKBP1ADPP4DPP8DPP9DPP7
SCHEMBL38652282 0.89 FKBP1A (0.53) FKBP1ADPP4DPP8DPP9DPP7
SCHEMBL8365666 0.89 DPP4 (0.61) FKBP1ADPP4DPP8DPP9DPP7
SCHEMBL7508784 0.89 DPP4 (0.61) FKBP1ADPP4DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL38652210 0.88 FKBP1A (0.53) FKBP1ADPP4DPP8DPP9DPP7
SCHEMBL13413212 0.88 FKBP1A (0.57) FKBP1ADPP4DPP8DPP9DPP7
Hydrochloric Acid SCHEMBL10403931 0.88 DPP4 (0.60) FKBP1ADPP4DPP8DPP9DPP7
SCHEMBL29290357 0.88 FKBP1A (0.56) FKBP1ADPP4DPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250032477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS VINCERX PHARMA GMBH (DE) 2025-01-30 US disclosed
US-20240423973-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS LERCHEN, HANS-GEORG (DE) 2024-12-26 US disclosed
US-20240408222-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDER VINCERX PHARMA GMBH (DE) 2024-12-12 US disclosed
CN-118556062-A Compounds, pharmaceutical compositions and methods for treating, preventing or managing hyperproliferative disorders 文赛克斯制药有限责任公司 2024-08-27 CN disclosed
EP-4412655-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDER Vincerx Pharma GmbH (DE) 2024-08-14 EP disclosed
EP-4412656-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS Vincerx Pharma GmbH (DE) 2024-08-14 EP disclosed
WO-2023057812-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDER VINCERX PHARMA GMBH (DE) 2023-04-13 WO disclosed
WO-2023057814-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS VINCERX PHARMA GMBH (DE) 2023-04-13 WO disclosed
WO-2023057814-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS VINCERX PHARMA GMBH (DE) 2023-04-13 WO disclosed
EP-0345867-A1 Novel synthetic, immunologically active peptides useful for the preparation of antimalarial vaccines ENIRICERCHE S.p.A. (IT) 1989-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240423973-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS PCNA, TP53, BRCA1 FKBP1A 2391/4885DPP4 3481/4885DPP8 1455/4885
US-20250032477-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS PCNA, TOP1, TOP2A FKBP1A 885/4885DPP4 2583/4885DPP8 1366/4885
US-20240408222-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDER PTK2, PCNA, CDK4 FKBP1A 1234/4885DPP4 2281/4885DPP8 1640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.