SCHEMBL729117

SCHEMBL729117

O=C(Nc1cccc(NC(=O)c2ccc(O)cc2)c1)c1ccc(O)cc1

nearest known ligand 0.71

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 4/20 0.71
KCNK9 Q9NPC2 3/20 0.71
MEN1 O00255 6/20 0.70
KMT2A Q03164 6/20 0.70
NQO2 P16083 1/20 0.69
TOP1 P11387 2/20 0.68
RAB9A P51151 3/20 0.67
TP53 P04637 2/20 0.67
NPC1 O15118 2/20 0.67
MAPK1 P28482 1/20 0.67
TOP2A P11388 1/20 0.65
TOP2B Q02880 1/20 0.65
LMNA P02545 1/20 0.63
MAPT P10636 1/20 0.63
SIRT1 Q96EB6 1/20 0.62
SNCA P37840 1/20 0.61
DEGS1 O15121 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3656361 0.92 NPC1 (0.78) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL28185509 0.88 NPC1 (0.76) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL28579555 0.88 NPC1 (0.76) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL27835354 0.88 NQO2 (0.59) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL29768474 0.88 NPC1 (0.76) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL24628731 0.88 NPC1 (0.71) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL14363224 0.88 MEN1 (0.73) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL14715832 0.86 KCNK3 (0.88) KCNK3KCNK9MEN1KMT2ARAB9A
SCHEMBL1603641 0.86 DEGS1 (0.79) KCNK3KCNK9MEN1KMT2ANQO2
SCHEMBL26897739 0.84 MEN1 (0.65) KCNK3KCNK9MEN1KMT2ATOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1692208-B1 WATER-SOLUBLE POLYHYDROXYAMINOETHER AND PROCESS FOR PREPARING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2016-10-05 EP disclosed
WO-2015107490-A1 ANTI-GEL AGENT FOR POLYHYDROXYETHERAMINES, GEL STABILIZED POLYHYDROXYAMINOETHER SOLUTIONS, AND METHODS FOR MAKING AND USING SAME CLEARWATER INTERNATIONAL, LLC (US) 2015-07-23 WO disclosed
US-20150197682-A1 ANTI-GEL AGENT FOR POLYHYDROXYETHERAMINES, GEL STABILIZED POLYHYDROXYETHERAMINE SOLUTIONS, AND METHODS FOR MAKING AND USING SAME Lubrizol Oilfield Solutions, Inc. 2015-07-16 US disclosed
US-8138257-B1 Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2012-03-20 US disclosed
US-7893136-B2 Water soluble co-polyhydroxyaminoether and solution thereof DOW GLOBAL TECHNOLOGIES, INC. (US) 2011-02-22 US disclosed
WO-2011016838-A1 POLYETHERAMINE NANOCOMPOSITE BARRIER COATINGS AND ARTICLES MADE THEREWITH INMAT INC. (US) 2011-02-10 WO disclosed
US-20100113690-A1 PROCESS FOR PREPARING WATER-SOLUBLE POLYHYDROXYAMINOETHER DOW GLOBAL TECHNOLOGIES, INC. (US) 2010-05-06 US disclosed
US-7678872-B2 Process for preparing water-soluble polyhydroxyaminoether DOW GLOBAL TECHNOLOGIES, INC. (US) 2010-03-16 US disclosed
US-20090005503-A1 PROCESS FOR PREPARING WATER-SOLUBLE POLYHYDROXYAMINOETHER DOW GLOBAL TECHNOLOGIES INC. (US) 2009-01-01 US disclosed
US-20080045642-A1 PROCESS FOR PREPARING WATER-SOLUBLE POLYHYDROXYAMINOETHER DOW GLOBAL TECHNOLOGIES INC. 2008-02-21 US disclosed
US-6512124-B1 N-(3,5-bis(4-hydroxybenzoyl)benzene)-4-fluoroisophthalimide. Aromatic polyimides (Pls) are well known, high-performance materials with widespread applications in the aerospace and electronics industries due to their excellent thermomechanical THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-01-28 US disclosed
EP-0929590-B1 HYDROXY-PHENOXYETHER POLYMER THERMOPLASTIC COMPOSITES DOW CHEMICAL CO (US) 2002-05-29 EP disclosed
US-6011111-A REINFORCING FIBERS; COMPOSITES CAN BE MOLDED INTO SHAPED ARTICLES USEFUL FOR STRUCTURAL MATERIALS AND PARTS BY CONVENTIONAL THERMOFORMING OR OTHER FABRICATION TECHNIQUES. THE DOW CHEMICAL COMPANY (US) 2000-01-04 US disclosed
US-5962093-A Thermally stable polyetheramines THE DOW CHEMICAL COMPANY (US) 1999-10-05 US disclosed
EP-0929590-A1 HYDROXY-PHENOXYETHER POLYMER THERMOPLASTIC COMPOSITES THE DOW CHEMICAL COMPANY (US) 1999-07-21 EP disclosed
WO-1998014498-A1 HYDROXY-PHENOXYETHER POLYMER THERMOPLASTIC COMPOSITES THE DOW CHEMICAL COMPANY (US) 1998-04-09 WO disclosed
US-5686551-A DIHYDROXYSTILBENES, DIGLYCIDYL ETHERS THE DOW CHEMICAL COMPANY (US) 1997-11-11 US disclosed
US-5464924-A Flexible films of polyethers with oxygen barriers THE DOW CHEMICAL COMPANY (US) 1995-11-07 US disclosed
US-5401814-A Catalytic reaction of a dihydric phenol and diepoxy compound and cationic ammonium or phosphonium compounds in solvents THE DOW CHEMICAL COMPANY (US) 1995-03-28 US disclosed
US-5391650-A Amorphous, low viscosity and self-curing; workability; molding materials; composites; adhesives; binders; coatings; heat resistance THE DOW CHEMICAL COMPANY (US) 1995-02-21 US disclosed