Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282692 | 0.92 | SMN1; SMN2 (0.47) | ALDH1A1POLBPKMPRKCDCFTR | |
| SCHEMBL7291760 | 0.89 | CYP1A2 (0.56) | ALDH1A1POLBPKMKDM4EHPGD | |
| SCHEMBL7291858 | 0.86 | PRKCH (0.44) | ALDH1A1POLBPRKCAPRKCDCFTR | |
| SCHEMBL11234893 | 0.85 | PDE3B (0.49) | ALDH1A1POLBKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7291097 | 0.82 | SMN1; SMN2 (0.48) | ALDH1A1POLBPKMCFTRKDM4E | |
| SCHEMBL7298318 | 0.81 | CNR1 (0.47) | ALDH1A1POLBCFTRKDM4EHPGD | |
| SCHEMBL7291890 | 0.81 | CYP1A2 (0.58) | ALDH1A1POLBPKMCFTRKDM4E | |
| SCHEMBL11251403 | 0.80 | PDE3B (0.50) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 | |
| SCHEMBL7293503 | 0.79 | PRKCD (0.48) | ALDH1A1PRKCAPRKCDCFTRKDM4E | |
| SCHEMBL7284126 | 0.77 | PDE3B (0.45) | ALDH1A1KDM4EHPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200024-B1 | 3-CYANO-PYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1992-07-01 | — | — | EP | disclosed |
| EP-0200024-A2 | 3-Cyano-pyridines, process for their preparation and their pharmaceutical use | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1986-11-05 | — | — | EP | disclosed |