⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763563 | 1.00 | — | — | |
| SCHEMBL9777662 | 0.76 | — | — | |
| SCHEMBL11037243 | 0.72 | — | — | |
| SCHEMBL191190 | 0.68 | — | — | |
| SCHEMBL6371601 | 0.68 | — | — | |
| SCHEMBL10745821 | 0.68 | — | — | |
| SCHEMBL7106992 | 0.68 | — | — | |
| SCHEMBL5491548 | 0.67 | — | — | |
| SCHEMBL11190421 | 0.63 | — | — | |
| SCHEMBL6211499 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153752-A1 | STEREOSELECTIVE SYNTHESIS OF INTERMEDIATES AND SYNTHESIS OF QUINAGOLIDS | FERRING B.V. (NL) | 2024-07-25 | — | — | WO | claimed |
| EP-0912553-A1 | BENZO[g]QUINOLINE DERIVATIVES | Novartis AG (CH) | 1999-05-06 | — | — | EP | claimed |
| WO-1998001444-A1 | BENZO[g]QUINOLINE DERIVATIVES | NOVARTIS AG (CH) | 1998-01-15 | — | — | WO | claimed |
| WO-2024153752-A1 | STEREOSELECTIVE SYNTHESIS OF INTERMEDIATES AND SYNTHESIS OF QUINAGOLIDS | FERRING B.V. (NL) | 2024-07-25 | — | — | WO | disclosed |
| WO-2024153752-A1 | STEREOSELECTIVE SYNTHESIS OF INTERMEDIATES AND SYNTHESIS OF QUINAGOLIDS | FERRING B.V. (NL) | 2024-07-25 | — | — | WO | disclosed |
| EP-0659430-A1 | Use of benzo[g]quinolines in the treatment of glaucoma and for the prevention of progressive atrophy of the optic nerve | SANDOZ LTD. (CH) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994007863-A9 | OCTAHYDRONAPHTHOQUINOLIZINES, AND METHODS OF MAKING AND USING THEREOF | — | 1994-06-09 | — | — | WO | disclosed |
| WO-1994007863-A1 | OCTAHYDRONAPHTHOQUINOLIZINES, AND METHODS OF MAKING AND USING THEREOF | NEW YORK UNIVERSITY (US) | 1994-04-14 | — | — | WO | disclosed |
| US-5298509-A | Octahydronaphthoquinolizines, and methods of making and using thereof | NEW YORK UNIVERSITY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5262422-A | Octahydrobenzo[g]quinoline | SANDOZ LTD. (CH) | 1993-11-16 | — | — | US | disclosed |
| EP-0512952-A1 | Octahydrobenzo (G) quinoline | SANDOZ LTD. (CH) | 1992-11-11 | — | — | EP | disclosed |
| EP-0512952-A1 | Octahydrobenzo (G) quinoline | SANDOZ LTD. (CH) | 1992-11-11 | — | — | EP | disclosed |
| EP-0246633-B1 | Trans-benzopyran-[4,3-b]-1,4-oxazine derivatives | WARNER-LAMBERT COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4792548-A | Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use | WARNER-LAMBERT COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0246633-A1 | Trans-benzopyran-[4,3-b]-1,4-oxazine derivatives | WARNER-LAMBERT COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |