⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292397 | 0.72 | — | — | |
| SCHEMBL10763563 | 0.72 | — | — | |
| SCHEMBL5491548 | 0.69 | — | — | |
| SCHEMBL10745821 | 0.67 | — | — | |
| SCHEMBL7106992 | 0.67 | — | — | |
| SCHEMBL9823953 | 0.66 | — | — | |
| SCHEMBL9777662 | 0.66 | — | — | |
| SCHEMBL9823784 | 0.66 | — | — | |
| SCHEMBL11190421 | 0.59 | — | — | |
| SCHEMBL191190 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142920-A2 | 6-Oxodecahydroquinolines and process for their preparation | ELI LILLY AND COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0013788-B1 | OCTAHYDRO-2H-PYRROLO(3,4-G)QUINOLINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ELI LILLY AND COMPANY (US) | 1983-04-27 | — | — | EP | disclosed |
| US-4311844-A | Octahydro-2H-pyrrolo[3,4,-g]quinolines | ELI LILLY AND COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| US-4282362-A | TREATING PARKINSON'S DISEASE, INHIBITORS OF PRE ACTIN SECRETION, DOPAMINE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4235909-A | DOPAMINE ANTAGONISTS, IN THE TREATMENT OF PARKINSON'S DISEASE | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| EP-0013788-A1 | Octahydro-2H-pyrrolo(3,4-g)quinolines, process for their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1980-08-06 | — | — | EP | disclosed |