Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377736 | 0.91 | ITGB3 (0.48) | ITGB3ITGA2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8382665 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8378306 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BKMT2A | |
| SCHEMBL8378304 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BKMT2A | |
| SCHEMBL7292420 | 0.81 | MIF (0.47) | ITGB3ITGA2BKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7291775 | 0.80 | ITGB3 (0.61) | ITGB3ITGA2BKMT2ASMN1; SMN2HRH3 | |
| SCHEMBL8377861 | 0.80 | ITGB3 (0.44) | ITGB3ITGA2BPOLB | |
| SCHEMBL8379152 | 0.77 | ITGB3 (0.48) | ITGB3ITGA2B | |
| SCHEMBL7293878 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BHTT | |
| SCHEMBL8382793 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656348-B1 | Aceric acid derivatives as medicaments | HOFFMANN LA ROCHE (CH) | 2000-05-03 | — | — | EP | claimed |
| US-5973188-A | Acetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-10-26 | — | — | US | disclosed |