Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295209 | 0.85 | ALOX15 (0.46) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL6140245 | 0.85 | ALOX15 (0.62) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL7292923 | 0.84 | ALOX15 (0.42) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Hydrochloric Acid SCHEMBL29588252 | 0.83 | ALOX15 (0.60) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL6710796 | 0.78 | ALOX15 (0.47) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL7296658 | 0.78 | APP (0.46) | ALOX15KDM4ERECQLHIF1AHSD17B10 | |
| SCHEMBL2058586 | 0.77 | SLC7A5 (0.59) | SLC7A5ESR1SLC6A2 | |
| SCHEMBL5598391 | 0.77 | SLC7A5 (0.59) | SLC7A5ESR1SLC6A2 | |
| SCHEMBL17062932 | 0.77 | SLC7A5 (0.59) | SLC7A5ESR1SLC6A2 | |
| SCHEMBL7303263 | 0.77 | TYR (0.47) | ALOX15ALOX12KDM4ERECQLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393781-B1 | Dopamine pro-drug | ZAMBON SPA (IT) | 1995-02-08 | — | — | EP | disclosed |
| US-5073547-A | DOPAMINE PRO-DRUG | SIMES SOCIETA ITALIANA MEDICINALI E SINTETICI S.P.A. (IT) | 1991-12-17 | — | — | US | disclosed |
| EP-0393781-A2 | Dopamine pro-drug | ZAMBON GROUP S.p.A. (IT) | 1990-10-24 | — | — | EP | disclosed |