Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182355 | 0.75 | MEN1 (0.31) | MEN1KMT2AKDM4EMAPTALPG | |
| SCHEMBL14182349 | 0.75 | KMT2A (0.50) | MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL10566339 | 0.72 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7286789 | 0.72 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL12848276 | 0.71 | — | — | |
| SCHEMBL7285751 | 0.69 | KMT2A (0.37) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10562070 | 0.69 | KMT2A (0.37) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL128525 | 0.68 | — | — | |
| SCHEMBL17198269 | 0.67 | FDPS (0.36) | MEN1KMT2AKDM4EMAPTALPG | |
| SCHEMBL22937086 | 0.67 | CACNA1C (0.51) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |