Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.48 |
| ▸ | MME | P08473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294088 | 1.00 | ACE (0.48) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7293059 | 0.96 | ACE (0.48) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7293054 | 0.96 | ACE (0.48) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7375555 | 0.92 | ACE (0.46) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7282391 | 0.90 | ACE (0.49) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7282410 | 0.90 | ACE (0.49) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7290234 | 0.90 | MME (0.55) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7291854 | 0.90 | MME (0.55) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL7290676 | 0.90 | MME (0.55) | ACEMMEALDH1A1KMT2AHPGD | |
| SCHEMBL9813914 | 0.90 | MME (0.55) | ACEMMEALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341081-B1 | Novel amino acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-07-05 | — | — | EP | claimed |
| EP-0341081-A2 | Novel amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-11-08 | — | — | EP | claimed |
| US-5317021-A | Analgesics, anticonvulsants | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-05-31 | — | — | US | disclosed |
| US-5202340-A | Analgesics, anticonvulsants, anxiolytic agents, inhibitors for enkephalinases | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| US-5017589-A | Analgesic, antianxiety, anticonvulsant | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |