Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | MME | P08473 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378387 | 0.96 | ACE (0.46) | ACEMME | |
| SCHEMBL7294083 | 0.92 | ACE (0.48) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7294088 | 0.92 | ACE (0.48) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7374787 | 0.90 | ACE (0.48) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7369849 | 0.90 | MME (0.47) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7374659 | 0.89 | MME (0.43) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7293054 | 0.89 | ACE (0.48) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7293059 | 0.89 | ACE (0.48) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7371152 | 0.88 | MME (0.42) | ACEMMEKMT2AALDH1A1HPGD | |
| SCHEMBL7373687 | 0.87 | MME (0.43) | ACEMMEKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341081-B1 | Novel amino acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-07-05 | — | — | EP | claimed |