SCHEMBL7294172

SCHEMBL7294172

COC(=O)ON=NOC(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.35
CA14 Q9ULX7 1/20 0.35
TSHR P16473 3/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
CRBN Q96SW2 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CA2 P00918 1/20 0.32
PTGS1 P23219 1/20 0.32
MMP12 P39900 1/20 0.32
HSD17B10 Q99714 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8464996 0.78
SCHEMBL27322751 0.75
SCHEMBL20796 0.73
SCHEMBL4748477 0.73 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2CA14TSHRKEAP1
SCHEMBL4971363 0.73
SCHEMBL7736984 0.73
SCHEMBL1179714 0.73 TSHR (0.46) ALDH1A1CA14TSHRHCAR2KDM4E
SCHEMBL8549706 0.73
Urea SCHEMBL28723467 0.72 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2CA14TSHRKEAP1
SCHEMBL1304238 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103193686-B Esterification method for preparing azodicarbonic acid Shangdong Normal University (CN) 2014-10-29 CN disclosed
CN-103193683-B Esterification method for preparing hydrogenated dialkyl azodicarbonic acid UNIV SHANDONG NORMAL 2014-07-09 CN disclosed
CN-103193683-A Esterification method for preparing hydrogenated dialkyl azodicarbonic acid UNIV SHANDONG NORMAL 2013-07-10 CN disclosed
CN-103193686-A Esterification method for preparing azodicarbonic acid UNIV SHANDONG NORMAL 2013-07-10 CN disclosed
EP-0293567-B1 Vascular anticoagulating proteins, DNA encoding them, process for their production and their use BOEHRINGER INGELHEIM INT (DE) 1996-01-31 EP disclosed
EP-0347766-B1 4,5,7,8-Tetrahydro-6H-thiazolo[5,4-d]azepines, their preparation and their use as medicaments THOMAE GMBH DR K (DE) 1994-05-25 EP disclosed
EP-0592791-A2 Tricyclic compounds and peptide derivatives thereof F. HOFFMANN-LA ROCHE AG (CH) 1994-04-20 EP disclosed
EP-0287076-B1 RECEPTOR OF THE MINOR RHINOVIRUS RECEPTOR GROUP BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1993-03-24 EP disclosed
EP-0188400-B1 OLIGOPEPTIDES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION CIBA-GEIGY AG (CH) 1992-07-08 EP disclosed
EP-0126430-B1 PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE CIBA-GEIGY AG (CH) 1991-08-28 EP disclosed
EP-0293567-A1 Vascular anticoagulating proteins, DNA encoding them, process for their production and their use BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1988-12-07 EP disclosed
WO-1988008032-A1 RECEPTOR FROM THE SMALL RHINOVIRUS RECEPTOR GROUP BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 1988-10-20 WO disclosed
EP-0287076-A1 Receptor of the minor rhinovirus receptor group BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) 1988-10-19 EP disclosed
WO-1988001276-A2 PROCESS FOR PRODUCING (Z)-17alpha-HALOGENVINYLSTEROIDS SCHERING AKTIENGESELLSCHAFT (DE) 1988-02-25 WO disclosed
EP-0188400-A2 Oligopeptides, intermediates and process for their preparation CIBA-GEIGY AG (CH) 1986-07-23 EP disclosed
EP-0168342-A1 Process for the preparation of thrombin inhibitors CIBA-GEIGY AG (CH) 1986-01-15 EP disclosed
EP-0046188-B1 PROCESS FOR THE PREPARATION OF ISOXAZOLINO-AZO COMPOUNDS BASF Aktiengesellschaft (DE) 1985-04-03 EP disclosed
EP-0126430-A2 Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use CIBA-GEIGY AG (CH) 1984-11-28 EP disclosed
EP-0085170-A2 Norbornan compounds, plant growth regulator containing them and their precursors BASF Aktiengesellschaft (DE) 1983-08-10 EP disclosed
EP-0046188-A1 Process for the preparation of isoxazolino-azo compounds BASF Aktiengesellschaft (DE) 1982-02-24 EP disclosed