SCHEMBL7294229

SCHEMBL7294229

CN1CCN(C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)CCCc2ccccn2)CC1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7295892 0.95 REN (0.53) REN
SCHEMBL7286389 0.94 REN (0.56) REN
SCHEMBL7287419 0.93 REN (0.60) REN
SCHEMBL7286827 0.93 REN (0.51) REN
SCHEMBL7294993 0.92 REN (0.53) REN
SCHEMBL7283881 0.91 REN (0.60) REN
SCHEMBL7293417 0.88 REN (0.54) REN
SCHEMBL7285416 0.87 REN (0.55) REN
SCHEMBL7284745 0.86 REN (0.61) REN
SCHEMBL7268886 0.86 REN (0.69) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5116835-A Hypotensive agents HOECHST AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed
EP-0372537-A2 Urea derivatives of dipeptides with enzyme-inhibiting properties, process to make them, compositions containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-13 EP disclosed