⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL731669 | 0.85 | ABAT (0.31) | — | |
| SCHEMBL49390 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL49388 | 0.84 | ALDH1A1 (0.32) | — | |
| SCHEMBL15810216 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL170796 | 0.74 | — | — | |
| SCHEMBL28213312 | 0.74 | ALDH1A1 (0.32) | — | |
| Urea SCHEMBL4898976 | 0.72 | ALDH1A1 (0.36) | — | |
| SCHEMBL3889301 | 0.70 | — | — | |
| SCHEMBL7856487 | 0.70 | — | — | |
| SCHEMBL8544052 | 0.69 | MEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8136676-B2 | a membrane or fibers composed of or coated with methoxyethyl methacrylate/2-/-di(ethylene glycol)ethyl ether methacrylate-2-(diethylamino)ethyl methacrylate terpolymer for the selective removal, reduction or separation of white blood cells and/or platelets from blood by passing blood through the medium | UNIVERSITY OF SOUTHAMPTON (GB) | 2012-03-20 | — | — | US | disclosed |
| US-20080190843-A1 | Polymers Useful as Medical Materials | UNIVERSITY OF SOUTHAMPTON (GB) | 2008-08-14 | — | — | US | disclosed |