Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7296576 | 0.99 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DCTSK | |
| SCHEMBL7301150 | 0.89 | PDE4B (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7295171 | 0.86 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7292161 | 0.86 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5964136 | 0.86 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7294704 | 0.86 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7302284 | 0.86 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7290286 | 0.85 | PDE4B (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7290554 | 0.85 | PDE4B (0.62) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7293355 | 0.84 | PDE4B (0.61) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511865-B1 | Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents | AMERICAN HOME PROD (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0511865-A1 | Phenyl pyrazolidinones as bronchodilators and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-11-04 | — | — | EP | claimed |