Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.82 |
| ▸ | RAB9A | P51151 | 5/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | GLA | P06280 | 1/20 | 0.76 |
| ▸ | ATM | Q13315 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | BTK | Q06187 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2346429 | 0.87 | MAPT (0.62) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL7296261 | 0.87 | RAB9A (0.78) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL26074396 | 0.86 | RAB9A (1.00) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL7295331 | 0.85 | RAB9A (0.67) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL28583973 | 0.85 | MAPT (0.88) | MAPTRAB9ANPC1ALDH1A1GLA | |
| Iodide SCHEMBL30758631 | 0.83 | MAPT (0.84) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL1041220 | 0.82 | RAB9A (0.64) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL7291942 | 0.82 | RAB9A (0.64) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL7292242 | 0.81 | RAB9A (0.69) | MAPTRAB9ANPC1ALDH1A1GLA | |
| SCHEMBL15652344 | 0.80 | RAB9A (0.61) | MAPTRAB9ANPC1ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358118-B1 | Phenylamides - process for their preparation as well as a drug containing those compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| US-5135949-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| EP-0358118-A1 | Phenylamides - process for their preparation as well as a drug containing those compounds | Roche Diagnostics GmbH (DE) | 1990-03-14 | — | — | EP | disclosed |