SCHEMBL729491

SCHEMBL729491

CC1CCCN(C(=O)CCCCC(N)=O)C1.NC(=O)CCCCC(=O)N1CCCCCC1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
POLB P06746 2/20 0.68
MAPT P10636 1/20 0.68
ALDH1A1 P00352 3/20 0.56
LMNA P02545 1/20 0.56
L3MBTL1 Q9Y468 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
HPGD P15428 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
NPC1 O15118 1/20 0.50
ATM Q13315 1/20 0.49
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
GAA P10253 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ITGB3 P05106 1/20 0.43
ITGA2B P08514 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1159944 0.95 KMT2A (0.74) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL15224183 0.88 KMT2A (0.67) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL20082373 0.83 KMT2A (0.74) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL15224184 0.83 KMT2A (0.74) MEN1KMT2APOLBMAPTALDH1A1
SCHEMBL928861 0.82 ATM (0.71) MEN1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL9715086 0.82 ATM (0.71) MEN1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL9939066 0.82 ATM (0.71) MEN1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL6906063 0.82 ATM (0.71) MEN1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL3067309 0.82 ATM (0.71) MEN1KMT2AALDH1A1L3MBTL1TDP1
SCHEMBL5907440 0.82 ATM (0.71) MEN1KMT2AALDH1A1L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2307482-B1 LONG-TERM HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS DU PONT (US) 2017-01-25 EP claimed
EP-2307480-B1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS DU PONT (US) 2016-08-17 EP claimed
WO-2016073045-A1 IMPROVED THERMOPLASTIC COMPOSITES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-05-12 WO claimed
US-20160122487-A1 THERMOPLASTIC COMPOSITES E. I. DU PONT DE NEMOURS AND COMPANY 2016-05-05 US claimed
EP-2307504-B1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS DU PONT (US) 2015-07-08 EP claimed
US-8445574-B2 Heat resistant thermoplastic articles including polyhydroxy polymers E I DU PONT DE NEMOURS AND COMPANY (US) 2013-05-21 US claimed
US-20120196961-A1 THERMOPLASTIC COMPOSITION WITH HYDROXY AMINO ACID HEAT STABILIZER E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-08-02 US claimed
US-20120196962-A1 THERMOPLASTIC MELT-MIXED COMPOSITION WITH HEAT STABILIZER E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-08-02 US claimed
EP-2459648-A2 HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS INCLUDING POLYHYDROXY POLYMERS E. I. du Pont de Nemours and Company (US) 2012-06-06 EP claimed
JP-2011529986-A 2011-12-15 JP claimed
WO-2010014801-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
WO-2010014810-A1 LONG-TERM HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
WO-2010014785-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
WO-2010014795-A1 THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed
US-20100028580-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100029820-A1 LONG-TERM HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100029819-A1 HEAT RESISTANT MOLDED OR EXTRUDED THERMOPLASTIC ARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100029821-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING CO-STABILIZERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
US-20100029815-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 US claimed
WO-2010014791-A1 HEAT RESISTANT THERMOPLASTIC ARTICLES INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-04 WO claimed