SCHEMBL1159944

SCHEMBL1159944

CC1CCCN(C(=O)CCCCC(N)=O)C1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.74
MEN1 O00255 4/20 0.74
POLB P06746 2/20 0.74
MAPT P10636 1/20 0.74
ALDH1A1 P00352 3/20 0.61
LMNA P02545 1/20 0.61
HPGD P15428 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
NPC1 O15118 1/20 0.50
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
CHRM3 P20309 1/20 0.47
GAA P10253 1/20 0.47
HSD17B10 Q99714 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 1/20 0.45
ATM Q13315 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGA2B P08514 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729491 0.95 MEN1 (0.68) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL15224183 0.92 KMT2A (0.67) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL20082373 0.87 KMT2A (0.74) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL15224184 0.87 KMT2A (0.74) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL8423209 0.86 MEN1 (0.88) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL14879717 0.86 MEN1 (0.88) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL7533923 0.86 MEN1 (0.88) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL29191667 0.85 KMT2A (1.00) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL15224143 0.83 ALDH1A1 (0.65) KMT2AMEN1POLBMAPTALDH1A1
SCHEMBL15224145 0.83 KMT2A (0.69) KMT2AMEN1POLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459648-A2 HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS INCLUDING POLYHYDROXY POLYMERS E. I. du Pont de Nemours and Company (US) 2012-06-06 EP claimed
WO-2011014548-A2 HEAT AGING RESISTANT POLYAMIDE COMPOSITIONS INCLUDING POLYHYDROXY POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-02-03 WO claimed
US-6531529-B2 Mixture of aromatic polyamide, organohalogen compound and addition polymer SOLVAY ADVANCED POLYMERS, L.L.C. 2003-03-11 US claimed
US-20010053819-A1 Flame retardant anti-drip polyamide compositions SOLVAY ADVANCED POLYMERS, LLC 2001-12-20 US claimed
US-6207745-B1 COMPOSITION COMPRISING HIGH TEMPERATURE POLYPHTHALAMIDE, HALOGEN-CONTAINING ORGANIC COMPOUND, ANTI-DRIP COMPONENT COMPRISING POLYMER FORMED FROM AT LEAST ONE ETHYLENICALLY UNSATURATED MONOMER AND AT LEAST ONE CARBOXYLIC ACID BP AMOCO CORPORATION 2001-03-27 US claimed
EP-0807665-B1 Flame retardant high temperature polyphthalamides having improved thermal stability BP AMOCO CORP (US) 2000-07-12 EP claimed
EP-0411774-B2 Improvements to multifilament apparel yarns of nylon DU PONT (US) 2000-06-21 EP claimed
EP-0986614-A1 FLAME RETARDANT ANTI-DRIP POLYAMIDE COMPOSITIONS BP AMOCO CORPORATION (US) 2000-03-22 EP claimed
WO-1999040157-A1 FLAME RETARDANT ANTI-DRIP POLYAMIDE COMPOSITIONS BP AMOCO CORPORATION (US) 1999-08-12 WO claimed
US-5925300-A ADDING A WATER SOLUBLE ADDITIVES COMPRISING CALCIUM, MAGNESIUM, OR ZINC SALTS OF DICARBOXYLIC ACIDS TO POLYMER BEFORE FORMING FIBER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-07-20 US claimed
EP-0535082-B1 FIBER-FORMING COPOLYAMIDE AND FIBERS PRODUCED THEREFROM DU PONT (US) 1994-07-27 EP claimed
US-5219503-A Controlled spinning E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-15 US claimed
EP-0536315-A1 IMPROVEMENTS IN NYLON FLAT YARNS. DU PONT (US) 1993-04-14 EP claimed
US-5202182-A Used in hosiery E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-04-13 US claimed
EP-0535082-A1 FIBER-FORMING COPOLYAMIDE AND FIBERS PRODUCED THEREFROM. DU PONT (US) 1993-04-07 EP claimed
US-5194578-A FIBER-FORMING COPOLYAMIDE FROM 2-METHYL-PENTAMETHYLENE DIAMINE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-16 US claimed
US-5137666-A Nylon 66 modified with nylon 6 monomer or 2-methyl-pentamethylenediamine; hosiery E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-11 US claimed
WO-1991019753-A2 FIBER-FORMING COPOLYAMIDE AND FIBERS PRODUCED THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-26 WO claimed
WO-1991019839-A1 IMPROVEMENTS IN NYLON FLAT YARNS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-26 WO claimed
EP-0411774-A1 Improvements to multifilament apparel yarns of nylon E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-02-06 EP claimed