Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292529 | 0.90 | CFTR (0.52) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL21561088 | 0.82 | KMT2A (0.60) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL7282590 | 0.81 | KDM4E (0.57) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL7291236 | 0.81 | CYP1A2 (0.54) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7296121 | 0.80 | CYP1A2 (0.53) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL23571100 | 0.78 | KMT2A (0.55) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15900575 | 0.74 | KDM4E (0.52) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL15900545 | 0.73 | IDH1 (0.59) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| Fumaric Acid SCHEMBL7483707 | 0.72 | ALDH1A1 (0.53) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL3453740 | 0.72 | CYP1A2 (0.42) | RXFP1KMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200024-A2 | 3-Cyano-pyridines, process for their preparation and their pharmaceutical use | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1986-11-05 | — | — | EP | disclosed |