Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294952 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BALOX15AOC3HRH3 | |
| SCHEMBL7294985 | 1.00 | ITGB3 (0.45) | ITGB3ITGA2BALOX15AOC3HRH3 | |
| SCHEMBL7294022 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BALOX15AOC3HRH3 | |
| SCHEMBL7294060 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BALOX15AOC3HRH3 | |
| SCHEMBL7294036 | 0.86 | ITGB3 (0.47) | ITGB3ITGA2BALOX15AOC3HRH3 | |
| SCHEMBL7295272 | 0.85 | AOC3 (0.43) | ITGB3ITGA2BALOX15AOC3HRH3 | |
| SCHEMBL7295259 | 0.85 | AOC3 (0.43) | ITGB3ITGA2BALOX15AOC3HRH3 | |
| SCHEMBL7297997 | 0.82 | ITGB3 (0.67) | ITGB3ITGA2BALOX15HRH3 | |
| SCHEMBL7298004 | 0.82 | ITGB3 (0.67) | ITGB3ITGA2BALOX15HRH3 | |
| SCHEMBL7298008 | 0.82 | ITGB3 (0.67) | ITGB3ITGA2BALOX15HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | claimed |
| EP-0609282-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1994-08-10 | — | — | EP | disclosed |
| WO-1993008181-A1 | CYCLOHEXANEACETIC ACID DERIVATIVES AS INHIBITORS OF FIBRINOGEN-DEPENDENT BLOOD PLATELET AGGREGATION | GLAXO GROUP LIMITED (GB) | 1993-04-29 | — | — | WO | disclosed |
| EP-0537980-A1 | Cyclohexaneacetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation | GLAXO GROUP LIMITED (GB) | 1993-04-21 | — | — | EP | disclosed |