SCHEMBL7295174

SCHEMBL7295174

COC(=O)[C@@H]1CCCN1C(=O)C1CCCCN1C(=O)C1CCc2ccccc2C1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.55
PREP P48147 10/20 0.48
ALOX5 P09917 1/20 0.43
FKBP1A P62942 2/20 0.43
AVPR2 P30518 1/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7302711 0.95 F2 (0.59) F2PREPALOX5AVPR2ALDH1A1
SCHEMBL7303542 0.92 F2 (0.49) F2PREPALOX5ALDH1A1CYP3A4
SCHEMBL7303538 0.92 F2 (0.49) F2PREPALOX5ALDH1A1CYP3A4
SCHEMBL7292823 0.83 PREP (0.67) F2PREP
SCHEMBL7292814 0.83 PREP (0.67) F2PREP
SCHEMBL7300952 0.83 PREP (0.63) F2PREP
SCHEMBL9050882 0.82 PREP (0.59) F2PREP
SCHEMBL7301169 0.82 PREP (0.70) PREP
SCHEMBL9049364 0.82 PREP (0.59) F2PREP
SCHEMBL9049367 0.82 PREP (0.59) F2PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0372484-B1 Condensed benzene derivative ZERIA PHARM CO LTD (JP) 1994-10-26 EP disclosed
US-5028604-A Cognition Activators ZERIA PHARMACEUTICAL CO., LTD. (JP) 1991-07-02 US disclosed
EP-0372484-A2 Condensed benzene derivative ZERIA PHARMACEUTICAL CO., LTD. (JP) 1990-06-13 EP disclosed