Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180175 | 0.90 | ADRB2 (0.46) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2815576 | 0.90 | ADRB2 (0.47) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2814774 | 0.90 | ADRB2 (0.46) | ADRB2 | |
| SCHEMBL3283078 | 0.90 | ADRB2 (0.48) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2815661 | 0.86 | ADRB2 (0.43) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2817025 | 0.86 | ADRB2 (0.43) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2815474 | 0.85 | ADRB2 (0.45) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2812553 | 0.84 | ADRB2 (0.45) | ADRB2 | |
| Trifluoroacetic Acid SCHEMBL2813024 | 0.83 | ADRB2 (0.41) | ADRB2 | |
| SCHEMBL524144 | 0.82 | ADRB2 (0.59) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011524897-A | — | — | 2011-09-08 | — | — | JP | claimed |
| EP-2303266-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A 4-HYDROXY-2-OXO-2, 3- DIHYDRO-1, 3-BENZOTHIAZOL-7-YL COMPOUND FOR MODULATION OF BETA2-ADRENORECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2011-04-06 | — | — | EP | claimed |
| WO-2009154562-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A 4-HYDROXY-2-OXO-2, 3- DIHYDRO-1, 3-BENZOTHIAZOL-7-YL COMPOUND FOR MODULATION OF BETA2-ADRENORECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | WO | claimed |