Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SCN1A | P35498 | 3/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | THPO | P40225 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287710 | 0.91 | CHRM2 (0.43) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7279920 | 0.91 | CHRM2 (0.41) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7286146 | 0.89 | CHRM2 (0.39) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7286499 | 0.89 | CHRM2 (0.41) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7293529 | 0.87 | CHRM2 (0.38) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7285932 | 0.87 | HRH1 (0.40) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7284798 | 0.87 | NPY1R (0.44) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7286354 | 0.87 | HRH1 (0.41) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| Hydrochloric Acid SCHEMBL7428599 | 0.86 | NPY1R (0.43) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL7433406 | 0.86 | PTGDR2 (0.37) | CHRM2SLC6A2SLC6A4SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262448-B1 | IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | HEUMANN PHARMA GMBH & CO (DE) | 1991-12-18 | — | — | EP | disclosed |