Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7428983 | 0.99 | PTGDR2 (0.36) | PTGDR2HRH1HTR2ACHRM2SLC6A2 | |
| SCHEMBL7286799 | 0.94 | SIGMAR1 (0.38) | PTGDR2HRH1HTR2ACHRM2SLC6A2 | |
| SCHEMBL7285523 | 0.94 | CYP19A1 (0.40) | PTGDR2HRH1HTR2ASIGMAR1ALDH1A1 | |
| SCHEMBL7285767 | 0.90 | PTGDR2 (0.34) | PTGDR2SLC6A2SLC6A4ALDH1A1CYP3A4 | |
| SCHEMBL7285350 | 0.90 | CYP19A1 (0.37) | — | |
| SCHEMBL7295447 | 0.86 | CHRM2 (0.41) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL7430483 | 0.85 | SLC6A2 (0.42) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL7977296 | 0.85 | PTGDR2 (0.43) | PTGDR2HRH1HTR2ACHRM2SLC6A2 | |
| SCHEMBL7285697 | 0.85 | CYP19A1 (0.38) | LMNACASR | |
| SCHEMBL7295465 | 0.85 | CYP19A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448765-B1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1994-08-17 | — | — | EP | claimed |
| EP-0448765-A1 | Use of guanidine derivatives for the manufacture of a medicament with NPY-antagonistic activity | HEUMANN PHARMA GMBH & CO (DE) | 1991-10-02 | — | — | EP | claimed |