SCHEMBL7295477

SCHEMBL7295477

NC(=NCCC(c1ccncc1)c1ccc(F)cc1)NCCCc1c[nH]cn1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7285354 0.95 NPY1R (0.40) NPY1R
SCHEMBL7304585 0.93 NPY1R (0.48) NPY1R
SCHEMBL7285534 0.92 KDM1A (0.43)
SCHEMBL7285709 0.90 NPY1R (0.41) NPY1R
SCHEMBL7286369 0.87 NPY1R (0.47) NPY1R
SCHEMBL9828417 0.86 KDM1A (0.47)
SCHEMBL7315384 0.85 NPY1R (0.49) NPY1R
SCHEMBL7300955 0.83 NPY1R (0.49) NPY1R
SCHEMBL7286809 0.83 KDM1A (0.43)
SCHEMBL7315185 0.82 EPHX2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262448-B1 IMIDAZOLYLGUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM HEUMANN PHARMA GMBH & CO (DE) 1991-12-18 EP disclosed