Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25C | P30307 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355795 | 0.84 | CDC25B (0.55) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL7301511 | 0.83 | ALDH1A1 (0.46) | CDC25BALDH1A1KDM4ECNR1HPGD | |
| SCHEMBL27924168 | 0.78 | TNF (0.49) | CDC25BALDH1A1CDC25ACDC25CCNR1 | |
| SCHEMBL16092097 | 0.78 | CDC25B (0.48) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL854153 | 0.78 | CDC25B (0.60) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL277672 | 0.77 | CDC25B (0.82) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL11788534 | 0.75 | CDC25B (0.57) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL28624739 | 0.74 | ALDH1A1 (0.47) | CDC25BALDH1A1CDC25ACDC25CHPGD | |
| SCHEMBL28209896 | 0.74 | ALDH1A1 (0.47) | CDC25BALDH1A1CDC25ACDC25CHPGD | |
| SCHEMBL697232 | 0.74 | CDC25B (0.63) | CDC25BALDH1A1KDM4ECDC25ACDC25C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0184550-A2 | 5-Amino-4-hydroxy valeryl amide derivatives | CIBA-GEIGY AG (CH) | 1986-06-11 | — | — | EP | disclosed |