SCHEMBL729625

SCHEMBL729625

CN(C)C(C)([C]=O)CCCCN

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.33
FDPS P14324 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729626 1.00 CHRM2 (0.33) CHRM2FDPS
SCHEMBL10522467 0.67
SCHEMBL10804336 0.66 FDPS (0.38) FDPS
SCHEMBL30156940 0.65 ODC1 (0.37) CHRM2FDPS
SCHEMBL181191 0.65 ODC1 (0.37) CHRM2FDPS
SCHEMBL157457 0.65 ODC1 (0.37) CHRM2FDPS
SCHEMBL10442786 0.64
Water SCHEMBL21225404 0.64 ODC1 (0.36) CHRM2FDPS
Hydrochloric Acid SCHEMBL21225312 0.64 BLM (0.39) FDPS
SCHEMBL31185767 0.64 FDPS (0.34) CHRM2FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138309-B2 Modified rubisco large subunit n-methyltransferase useful for targeting molecules to the active-site vicinity of ribulose-1,5-bisphosphate UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2012-03-20 US disclosed
US-20110166208-A1 Nucleotide and Amino Acid Sequences for Calmodulin Protein Methyltransferase UNIVERSITY OF KENTUCKY (US) 2011-07-07 US disclosed
US-20090070901-A1 Modified rubisco large subunit n-methyltransferase useful for targeting molecules to the active-site vicinity of ribulose-1, 5-bisphosphate UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2009-03-12 US disclosed
US-20070169213-A1 Method rubisco large subunit n-methyltransferase useful for targeting molecules to the active-site vicinity of ribulose-1, 5-bisphosphatet UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2007-07-19 US disclosed
WO-2004101751-A2 A MODIFIED RUBISCO LARGE SUBUNIT ∈N-METHYLTRANSFERASE USEFUL FOR TARGETING MOLECULES TO THE ACTIVE-SITE VICINITY OF RIBULOSE-1, 5-BISPHOSPHATE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2004-11-25 WO disclosed
US-6245541-B1 REDUCTION OF ATMOSPHERIC CARBON DIOXIDE DURING PHOTOSYNTHESIS; POST-TRANSLATIONAL PROTEIN METHYLATION IN PLANTS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION 2001-06-12 US disclosed
EP-0948253-A1 ISOLATED SPINACH RUBISCO LARGE SUBUNIT N-METHYLTRANSFERASE University of Kentucky Research Foundation (US) 1999-10-13 EP disclosed
US-5908972-A Isolated spinach ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit .sup.ε N-methyltransferase and method of inactivating ribulose-1,5-bisphosphatase carboxylase/oxygenase large subunit .sup.ε N-methyltransferase activity UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1999-06-01 US disclosed
US-5866394-A CATALYZE METHYLATION OF LYSINE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1999-02-02 US disclosed
WO-1998004116-A9 ISOLATED SPINACH RUBISCO LARGE SUBUNIT N-METHYLTRANSFERASE 1998-06-11 WO disclosed
US-5723752-A GENETIC ENGINEERING UNIVERSITY OF KENTUCKY (US) 1998-03-03 US disclosed
WO-1998004116-A1 ISOLATED SPINACH RUBISCO LARGE SUBUNIT N-METHYLTRANSFERASE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1998-02-05 WO disclosed